Prof. Qiu Deyou's research work mainly includes investigating on the molecular mechanism of taxol biosynthesis and its regulation. His purpose is to obtain cell lines or transgenic plants with significantly improved taxol content through genetic engineering or synthetic biology approach. The molecular mechanism of taxol biosynthesis induced by MeJA in Taxus cell line was studied and a taxoid 9α-hydroxylase was identified from Ginkgo biloba.
Qiu Deyou, Pan Xiaoping, Wilson Iain W, Li Fenglan, Liu Min, Teng Wenjing, Zhang Baohong. 2009. High throughput sequencing technology reveals that the taxoid elicitor methyl jasmonate regulates microRNA expression in Chinese yew (Taxus chinensis). Gene, 436(1-2):37-44.
Guiling Sun., Yanfang Yang., Fuliang Xie, Jian-Fan Wen, Jianqiang Wu, Iain W. Wilson, Qi Tang, Hongwei Liu, Deyou Qiu. 2014. Deep Sequencing Reveals Transcriptome Re-Programming of Taxus x media Cells to the Elicitation with Methyl Jasmonate. PLoS ONE, 8(4): e62865.
Yang Yanfang, Zhao Hainan, Roberto A Barrero, Zhang Baohong, Sun Guiling, Wilson Iain W, Xie Fuliang, Walker Kevin D, Parks Joshua W, Bruce Robert, Guo Guangwu, Chen Li, Zhang Yong, Huang Xin, Tang Qi, Liu Hongwei, Bellgard Matthew I, Qiu Deyou, Lai Jinsheng, Hoffman Angela. 2014. Genome sequencing and analysis of the paclitaxel-producing endophytic fungus Penicillium aurantiogriseum NRRL 62431. BMC Genomics, 15: 69.
Zhang Nan, Han Zhentai, Sun Guiling, Hoffman Angela, Wilson Iain W, Yang Yanfang, Gao Qian, Wu Jianqiang, Xie Dan, Dai Jungui, Qiu Deyou. 2014. Molecular cloning and characterization of a cytochrome P450 taxoid 9á-hydroxylase in Ginkgo biloba cells. BBRC, 443: 938-943.
Lu Qiang, Shao Fenjuan, Macmillan Colleen, Wilson Iain W, van der Merwe Karen, Hussey Steven G, Myburg Alexander A, Dong Xiaomei, Qiu Deyou. 2018. Genome-wide analysis of the lateral organ boundaries domain (LBD) gene family in Eucalyptus grandis reveals members that differentially impact secondary growth. Plant Biotechnol J, 16(1):124-136.
Zhang Lisha, Sun Xiaomei, Wilson Iain, Shao Fenjuan, Qiu Deyou. 2019. Identification of the genes involved in anthocyanin biosynthesis and accumulation in Taxus chinensis. Genes, 10: E982.
Shao Fenjuan, Zhang Lisha, Guo Juan, Liu Xiaochun, Ma Wenhui, Wilson Iain W, Qiu Deyou. 2019. A comparative metabolomics analysis of the components of heartwood and sapwood in Taxus chinensis (Pilger) Rehd; Sci Rep. 9: 17647.
Zhang Kaikai, Fan Wei, Huang Zhongwen, Chen Duanfen, Yao Zhiwang, Li Yunfeng, Yang Yanfang, Qiu Deyou. 2019. Transcriptome analysis identifes novel responses and potential regulatory genes involved in 12-deoxyphorbol-13-phenylacetate biosynthesis of Euphorbia resinifera. Industrial Crops & Products, 135:138-145.
Hu Xinling, Zhang Lisha, Wilson Iain W, Shao Fenjuan, Qiu Deyou. 2020. The R2R3-MYB transcription factor family in Taxus chinensis: identification; characterization; expression profiling and posttranscriptional regulation analysis. Peer J, 8:e8473.
Shao Fenjuan, Sun Xiaochen, Wu Wenli, Qiu Deyou. 2021. A comparative analysis of differential N6-methyladenosine (m6A) modification between non-transgenic and LBD15 overexpressing Poplar 84 K plants. Tree Genetics & Genomes, 17(5):39.
Shao Fenjuan, Wilson Iain W, Qiu Deyou. 2021. The Research Progress of taxol in Taxus. Current Pharmaceutical Biotechnology, 22(3): 360-366.
Sun Xiaochen, Wu Wenli, Yang Yanfang, Wilson I, Shao F, Qiu Deyou. 2022. Genome-Wide Identification of m6A Writers, Erasers and Readers in Poplar 84K. Genes, 13(6): 1018.
Wu Wenli, Sun Xiaochen, Wilson Iain, Jiang Luyuan, Jiang Xiaoyang, Shao Fenjuan, Qiu Deyou. 2024. Effects of ferrous sulfate and methyl jasmonate treatment on the content of 2‑(2‑phenethyl) chromones in Aquilaria sinensis. Plant Cell, Tissue and Organ Culture (PCTOC), 156:51.
